The knee is the largest joint in the body and is considered
the most complicated one. It enables hinge and rotator movements at it forms
the connection between the upper and lower leg. Sometimes, the function of the
knee can be affected by metabolic disorders. A metabolic disorder occurs when
there is an alteration in normal metabolic process due to abnormal chemical
reactions. This leads to an imbalance in the body metabolism as you will have
too much or too little of essential substances.
The actual causes of metabolic disorders that affect the knee
are unknown. However, we can still seek to understand the signs and symptoms of
these disorders.
Gout
It is a form of acute arthritis which causes severe pain and
swelling in the joints such as the knee, ankle, and heel. It is an inflammatory
condition which is characterized by intense pain, swelling, and redness of the knee
joint. Gout develops due to increased level of uric acid in the blood or
hyperuricemia.
The common symptoms include Pain, Tenderness, Redness, Warmth
and swelling of the knee joint, Inflammation, Mild fever.
Osteomalacia
Osteomalacia is the softening of the bones that occur due to
inadequate levels of phosphate, calcium and vitamin D or resorption of calcium.
Osteomalacia is commonly caused by vitamin D deficiency. The other two causes
are insufficient calcium absorption from the intestine and phosphate deficiency
caused by increased renal losses. The signs and symptoms include diffused
joints and bone pain, muscle weakness, difficulty walking, hypocalcemia, pelvic
flattening and bending of the bones.
Chondrocalcinosis
Chondracalcinosis is characterized by deposits of calcium
pyrophosphate dehydrate crystals in one or more joint cartilages resulting in
damage to the joints. It commonly affects the knee. It occurs in a hereditary form
associate with metabolic disorders. The sign and symptoms include swelling, stiffness
and pain.
Paget’s
disease
Paget’s disease occurs due to excessive breakdown or
formation of bone. This causes the bone to grow larger and weaker than normal,
leading to the risk of fracture. The disease may affect more than one bone and
occurs commonly in the knees, skull and hip joints, etc. The sign and symptoms
include pain, bending of the bones and tingling and weakness.
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